Patrick Mahomes and the Kansas City Chiefs will host Russell Wilson and the Denver Broncos on Sunday. The Broncos are fresh off a 51-14 defeat at the hands of the Los Angeles Rams, leading to the dismissal of rookie head coach Nathaniel Hackett, who had seemingly been on the hot seat since the season began. Life won’t get easier for Denver with the Chiefs up next. The Chiefs are among the favorites to win the Super Bowl and Mahomes is a heavy favorite to win NFL MVP. Andy Reid’s team most recently dispatched the Seattle Seahawks and are 13-point favorites in the latest Week 17 NFL odds at Caesars Sportsbook. Which Week 17 NFL lines should you target with your Week 17 NFL bets? Before you make any Week 17 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 17 of the 2022 NFL season on an incredible 158-113 run on top-rated NFL picks that dates back to the 2017 season.
The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is WAY UP.
Now, the model has locked in five confident NFL best bets for Week 17. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 17 NFL picks at SportsLine.
Top Week 17 NFL picks
After simulating every game 10,000 times, the model is high on the San Francisco 49ers (-10) to cover against the Las Vegas Raiders. San Francisco has allowed an average of 290.3 yards of offense per game, the best mark in the league. It is the only team allowing an average of fewer than 300 yards. While the Raiders are capable of scoring points, San Francisco’s suffocating defense should make lighting up the scoreboard difficult.
Given that the Niners can now also score in bunches with Brock Purdy’s emergence, asking any team to keep the score close with San Francisco is a tall task. That is one reason the 49ers are covering the spread in more than 50% of simulations. See which other NFL parlay picks to make here.
How to make Week 17 NFL parlays
The model also jumped on four other NFL matchups where it says the line is way off, including a pair of underdogs that have a chance to win outright. You can only see the model’s NFL Week 17 best bets and parlay at SportsLine.
What are the model’s top Week 17 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 17 NFL best bets from a model on a 158-113 run on its top-rated picks, and find out.
